Volunteers required for whole genome sequencing – Will you participate?

Today the UK has launched a personal genome project, urging 100,000 people to contribute their genetic information and have their genome sequenced to be put on public record. Is this a big step in the advancement of sequencing huge sample sizes? Or is making our entire genome available  to anyone online a step too far?

Our DNA is what makes us who we are; a sequence of bases in each and every one of our cells which contains the code to making what we see in the mirror every morning. It is possible for someone to look at your DNA and determine almost everything about us; the colour of our hair, our eyes or any genetic diseases we may have or be prone to, without ever having actually laid their eyes on us.

Whilst it would have previously been near impossible for many people to gain access to our DNA, a new initiative has been set in place by The Personal Genome Project UK (PGP-UK) urging 100,000 volunteers to donate their genetic information for their genome to be sequenced. This has already been undertaken by other countries, including America in 2005. However, this is the first time a project like this has been attempted in the UK, and many sceptics have their doubts.

The aim of those conducting this project is to accelerate researchers understanding of genes, both normal and defective, as well as how different environmental influences can affect those genes. However, the majority of companies sponsoring this research (one of which being google) are hoping to use this data for commercial exploitation, to specifically target advertising for drugs that each of us may need, based on our genetic code.

This is one reason why this project in controversial, but many also have issues with the broad spectrum of individuals who will be able to view your genetic code. Whilst names and addresses will not be included on record, the research group involved has warned that the security of participants is not guaranteed, and they could potentially be identified.

Because of this, a number of tests are included in the application of those who are applying to be involved, in which only a score of 100% will be accepted, which is designed to ensure that all those involved fully understand the potential risks.

If you were decide to join the project, and then be accepted, you will receive a kit to take cheek swabs, and also asked to attend a clinic to provide more extensive samples, with your genetic information published within a month.

It is hoped that this sort of extensive record of so many peoples genomes will allow for a number of major diseases, which have a large effect on public health, to be linked to genes which have previously been unidentified. This would be crucial information for those researching therapies for these diseases, and could dramatically advance our understanding of them.

Do you think you’d be interested in taking part in this project? Or do you think that having this kind of information about yourself on public record is a step too far? I for one know I’m definitely going to be signing up.